✅ What are the medications for high blood pressure can cause cough
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What are the medications for high blood pressure can cause a cough?
High blood pressure (arterial hypertension) is a widespread disease, which can eventually lead to serious complications such as heart attack, stroke, or kidney failure be liable. For the treatment of various groups of Drugs are used, some of which, however, as a side effect of a dry cough can trigger.
Drugs that can cause cough
ACE inhibitors (Angiotensin‑converting enzyme inhibitor)
This drug group is one of the most common triggers of a drug-induced cough. Among the well-known representatives:
Lisinopril
Enalapril
Ramipril
Captopril
The cough occurs in 10-20% of patients with ACE‑inhibitor use, and is often dry, lovely and durable. It can occur at any time during the therapy, but usually within the first few weeks or months.
Pathomechanism: ACE inhibitors inhibit the enzyme for the removal of substances such as Bradykinin is responsible. The resulting increased concentration of Bradykinin in the respiratory tract, irritating the nerve endings, triggering the cough reflex.
ARB (Angiotensin II receptor blockers)
This group includes substances like:
Losartan
Valsartan
Candesartan
Compared to ACE‑inhibitors, ARB cause significantly less cough (<5% of the cases), thus, are considered as an Alternative in patients who respond to ACE inhibitors, with cough.
Differential diagnosis and Management
In the event of a persistent cough during an anti-hypertensive therapy, the following steps should be taken:
To the exclusion of other possible causes:
Diseases of the respiratory system (e.g. Asthma, COPD)
Infections of the respiratory tract
Heart failure with pulmonary edema
Reflux disease
Medication review:
Determination of whether a ACE is taken inhibitor
Analysis of other possible drugs interactions
Therapy adjustment:
In cases in which the connection between ACE inhibitors and cough:
Discontinuation of the ACE Inhibitor
Switching to an ARB or other antihypertensive agent (e.g., calcium channel blockers, thiazide diuretic)
Observation:
The cough subsides, usually within 1-4 weeks after Discontinuation of the drug.
Conclusion
A dry cough may occur as a known side‑effect, in particular when taking ACE inhibitors. This reaction by the pharmacological mechanism of action of these classes of compounds is explained. In cases of suspected drug-related cough is a careful differential diagnosis is necessary, followed by a targeted adjustment of hypertension therapy. The change to the ARB, or other antihypertensive agents often allows the continuation of an effective reduction in blood pressure without coughing load.
Note: Prior to any Change in medication, a doctor's consultation is mandatory. Independent Discontinuation of Hypertension drugs can be dangerous.
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