✅ Research Institute for complex problems of cardiovascular diseases
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Research Institute for complex problems of cardiovascular diseases: Innovative approaches in research and therapy
Dasusgehend of the global challenge posed by cardiovascular disease (CVD) has been established in the research Institute for complex problems of cardiovascular diseases. The Institute aims to investigate the multifactorial causes of these diseases, systematically, and to develop innovative therapeutic approaches tailored to individual patient characteristics.
Focus of the research
The fields of action of the Institute include several areas of focus:
The genetic and molecular mechanisms. By means of high-throughput sequencing and bioinformatic analysis of genetic risk factors that contribute to diseases such as atherosclerosis, heart failure, or arrhythmic disorders. A special focus of the investigation is not considered epigenetic changes, and the role of non-coding RNA molecules.
Predictive modeling and AI applications. The Institute develops machine learning algorithms to the individual's risk for heart attack or stroke, a more precise estimate. Data based on multi-modal data, including electronic health records, imaging data (e.g., Cardiac MRI) and biochemical markers.
Personalized Therapy Concepts. On the Basis of the findings of personalized treatment strategies will be developed. These include targeted pharmacotherapy, minimally invasive procedures for heart valve repair, as well as innovative approaches of regenerative medicine (e.g., stem-cell therapy).
Prevention and Public Health. The Institute is involved in epidemiological studies, to evaluate the effectiveness of prevention measures (e.g., lowering blood pressure, lowering cholesterol, lifestyle changes), and evidence-based recommendations for health policy to derive.
Methodological Approach
The research at the Institute follows an interdisciplinary approach that integrates the following methods:
In‑vitro and in‑vivo model systems (e.g., transgenic mouse models);
Clinical intervention trials (Phase II/III);
Big Data analysis with the methods of Deep Learning;
Multi-centric cohort studies with long-term observation.
International networking and Transfer
The Institute maintains close cooperation with leading institutions in Europe and North America. The results are regularly published in prestigious journals and in the clinical practice. In addition, the Institute offers a comprehensive training program for young scientists:indoor and clinicians:the inside.
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Through the systematic exploration of complex cardiovascular diseases, the Institute opens new perspectives for the prevention, diagnosis and therapy. The long-term goal is to improve the quality of life and life expectancy of patients around the world in a sustainable way.
Ang pagkontrol sa presyon ay isang napakahalagang gawain, dahil ang pag-inom ng mga tableta na nakakatulong sa pagpapanatili ng normal na mga indikador ay maaaring magbigay ng araw-araw na komportableng buhay, upang maiwasan ang panganib ng hypertensive crisis, atake sa puso, at stroke. Ang mga gamot para sa kontrol ng presyon ay medyo malawakang makukuha sa mga botika, pero tanging ang doktor lang ang makakapili ng tamang gamot na angkop sa therapy. Lahat ng grupo ng gamot para pababain ang presyon ay may iba't ibang mekanismo ng epekto, side effects, at may kaunting posibilidad ng pagkadepende. Ang tamang pagpili ng gamot ay nagbibigay ng mabilis at tuloy-tuloy na resulta, at ang eksperimento sa sarili sa pag-inom ng gamot ay may mataas na posibilidad ng biglaang karamdaman, sakit sa puso at daluyan ng dugo, at sa matinding kaso, maaaring magdulot ng kamatayan.
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